| ImmunoMine™
is Viventia’s proprietary high-throughput antibody
screening platform which ImmunoMine™ rapidly characterizes monoclonal
antibodies for their therapeutic potential. Viventia routinely screens
immune libraries containing hundreds of thousands of antibodies
created from the B cells of cancer patients.
Viventia has incorporated many state-of-the-art high-throughput
technologies into ImmunoMine™, such as fluorescence
macro-confocal live cell screening, multiplexed ELISA, Fluorescence
Activated Cell Sorting (FACS), and human tissue microarrays.
The ImmunoMine™ platform consists of a rapid screening
‘funnel’, built upon increasingly more rigorous
tests designed to rapidly sort therapeutically promising
tumor-specific antibodies from those antibodies that react
with normal cells. Antibodies that successfully complete
ImmunoMine™ screening are added to Viventia’s
growing portfolio of tumor-selective human monoclonal antibodies
as potential drug development prospects.
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